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Los Alamos Science No. 20, 1992
The Human Genome Project
The human genome, the DNA content in each of our cells, presents us with a vast frontier containing answers to many questions about how we evolved, how we are related to other living things, and how we differ from one another. The Human Genome Project is opening up that territory to our understanding. LANL scientists were instrumental in getting the DOE involved in this project and in this volume present an introduction to the tools of genetics and molecular biology and to the philosophy and early accomplishments of the Project. At the time the volume was written, scientists and the public were anticipating the new genetic knowledge while physicians, lawyers, social scientists, and philosophers were anticipating the impact of that information on our institutions, our health care, and our individual lives. As the cover illustration suggests, the Human Genome Project is ushering in a future in which we are more aware of both our human potential and limitation. |
Table of Contents | PDF Size | Cover page and Editor’s Note
| 612 kB | The Los Alamos Center for Human Genome Studies
| 419 kB | Table of Contents
| 132 kB | Understanding Inheritance: An Introduction to Classical and Molecular Genetics Robert P. Wagner | 12376 kB | Mapping the Genome: The Vision, the Science, The Implementation; What is the Genome Project? A round table with David Baltimore, David Botstein, David R. Cox, David J. Galas, Leroy Hood, Robert K. Moyzis, Maynard V. Olson, Nancy S. Wexler, and Norton D. Ziner | 6968 kB | Maps, Markers, and the Five-Year Goals
| 7882 kB | Technological Challenges in the Genome Project
| 3944 kB | Implications for Biology and Society
| 3792 kB | The Mapping of Chromosome 16 Norman A. Doggett | 6602 kB | DNA Libraries: Recombinant Clones for Mapping and Sequencing Larry L. Deaven | 6671 kB | Computation and the Genome Project – A Shotgun Wedding James W. Fickett | 6675 kB | Rapid DNA Sequencing Based on Single-Molecule Detection Lloyd M. Davis, Frederick R. Fairfield, Mark L. Hammond, Carol A. Harger, James H. Jett, Richard A. Keller, et. Al | 2889 kB | Members of the Human Genome Center at Los Alamos National Laboratory
| 1062 kB | ELSI: Ethical, Legal, and Social Implications of the Human Genome Project Gerald Friedman and Richard Reichelt | 1667 kB | An Invitation to Genetics in the 21st Gentury A round table with David Baltimore, David Botstein, Leon Botstein, Robert K. Moyzis, James D. Watson, Nancy S. Wexler | 2878 kB | Human Genome Project Glossary
| 1413 kB |
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