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Los Alamos Science No. 18, 1989
AIDS Research
| In the late 1980's, before it was known that all people are vulnerable to HIV/AIDS, various members of LANL's Theoretical Division began to research basic questions about the growth of the AIDS epidemic and the evolutionary origins of the deadly virus. They developed a risk-based model outlining the growth of the epidemic, who is at risk, and what intervention strategies would be most effective. To trace the evolution of the virus and the rate at which it was mutating, LANL scientists also established a DNA Sequence Database for HIV. This volume discusses these topics and also includes a tutorial, "AIDS Viruses of Animals and Man," which explains how retroviruses, known as lentiviruses, act as parasites of the immune system and discusses the prospects for an HIV vaccine. Since publication of the volume, research on the mutation of the HIV virus and the development of treatment strategies has continued at LANL (see article in 60th anniversary volume). |
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